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About PepCyber:P~Pep
  • PepCyber :P~Pep is the largest public database of human protein-protein interactions mediated by phosphoprotein binding domains (PPBDs).
  • Current release: v. 1.2 (May 2010), includes 11,269 records of interactions between 387 PPBD proteins and 1,471 substrate proteins, curated from 4,852 published studies.
  • Please direct questions and comments to
  • Gong, W., Zhou, D., Ren, Y., Wang, Y., Zuo, Z., Shen, Y., Xiao, F., Zhu, Q., Hong, A., Zhou, X., Gao, X and Li, T. (2008) PepCyber:P~PEP: a database of human protein protein interactions mediated by phosphoprotein-binding domains. Nucleic Acids Res , 36 , D679-683. [PubMed] [Full text]
  • Wan, J., Kang, S., Tang, C., Yan, J., Ren, Y., Liu, J., Gao, X., Banerjee, A., Ellis, L.B. and Li, T. (2008) Meta-prediction of phosphorylation sites with weighted voting and restricted grid search parameter selection. Nucleic Acids Res . [PubMed] [Full text]
    Related databases
  • BOND (formerly BIND), by Unleashed Informatics.
  • DIP, developed at the University of California Los Angeles.
  • DOMINO, developed at the University of Rome Tor Vergata, Italy.
  • ELM, by Eukaryotic Linear Motif (ELM) consortium.
  • HPRD , developed at Institute of Bioinformatics, Bangalore, India and Johns Hopkins University.
  • Phospho.ELM, by Eukaryotic Linear Motif (ELM) consortium.
  • Scansite, developed at Massachusetts Institute of Technology.
  • STRING, by European Molecular Biology Laboratory (EMBL) and University of Zürich (UniZH)
    Please choose from the following options:
    PPBD Classes Read about the 10 PPBD classes, including descriptions about the length, structures, representative instances and reported binding specificity for each PPBD class.
    PPBD Proteins Browse PPBD-containing proteins by their gene symbol or synonym, to get detailed information about these proteins.
    Search Interactions Search PPBD-PPEP interactions by PPBD classes, PPBD protein names or synonyms, accessions in NCBI or Swiss-Prot, PPEP sequences or concerned pathways.
    Tutorial View a demonstration about the structure and utility of this database server.
    Glossary Read explanations of the terms and abbreviations used in the web site.
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